Summary: We previously reported the recovery of five ST11 carbapenem resistant hypervirulent Klebsiella pneumoniae (CR-HvKP) strains that harbored pLVPK-like virulence plasmids, yet molecular mechanisms underlying acquisition of virulence plasmid by ST11 K.pneumoniae have not been characterized.In this study, we showed that virulence plasmids in th
Kinesins, the microtubule-dependent mechanochemical enzymes, power a variety of intracellular movements.Regulation of read more Kinesin activity and Kinesin-Cargo interactions determine the direction, timing and flux of various intracellular transports.This review examines how phosphorylation of Kinesin subunits and adaptors influence the traffic d
The present study of ambiguity at the syntactic level in the English language focuses on its resourceful applications in the creation koip share price of jokes.Such ambiguity is therefore regarded as something to be exploited in language rather than avoided.One important conclusion will be that British humour should not be regarded as "strange" by
The growth hormone secretagogue receptor (GHSR) signals in response to ghrelin, but also acts via ligand-independent mechanisms that include either constitutive activation or interaction with other G protein-coupled receptors, such as the dopamine 2 receptor (D2R).A key target of GHSR in neurons is voltage-gated calcium read more channels type 2.2
Lung cancer is one of the deadliest, most aggressive cancers.Abrupt changes in gene expression represent an important challenge to understand and fight the disease.Gene co-expression networks (GCNs) have read more been widely used to study the genomic regulatory landscape of human cancer.Here, based on 1,143 RNA-Seq experiments from the TCGA collab